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Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases
Polyadenylation of nascent RNA by poly(A) polymerase (PAP) is important for 3′ end maturation of almost all eukaryotic mRNAs. Most mammalian genes harbor multiple polyadenylation sites (PASs), leading to expression of alternative polyadenylation (APA) isoforms with distinct functions. How poly(A) po...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5587728/ https://ncbi.nlm.nih.gov/pubmed/28911096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx560 |
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