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Rate-limiting steps in transcription dictate sensitivity to variability in cellular components

Cell-to-cell variability in cellular components generates cell-to-cell diversity in RNA and protein production dynamics. As these components are inherited, this should also cause lineage-to-lineage variability in these dynamics. We conjectured that these effects on transcription are promoter initiat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mäkelä, Jarno, Kandavalli, Vinodh, Ribeiro, Andre S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587725/
https://ncbi.nlm.nih.gov/pubmed/28878283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11257-2
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