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Temperature-Dependent Model of Multi-step Transcription Initiation in Escherichia coli Based on Live Single-Cell Measurements

Transcription kinetics is limited by its initiation steps, which differ between promoters and with intra- and extracellular conditions. Regulation of these steps allows tuning both the rate and stochasticity of RNA production. We used time-lapse, single-RNA microscopy measurements in live Escherichi...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Oliveira, Samuel M. D., Häkkinen, Antti, Lloyd-Price, Jason, Tran, Huy, Kandavalli, Vinodh, Ribeiro, Andre S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085040/
https://ncbi.nlm.nih.gov/pubmed/27792724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005174
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