A TCR-based Chimeric Antigen Receptor

Effector T cells equipped with engineered antigen receptors specific for cancer targets have proven to be very efficient. Two methods have emerged: the Chimeric Antigen Receptors (CARs) and T-cell Receptor (TCR) redirection. Although very potent, CAR recognition is limited to membrane antigens which...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Walseng, Even, Köksal, Hakan, Sektioglu, Ibrahim M., Fåne, Anne, Skorstad, Gjertrud, Kvalheim, Gunnar, Gaudernack, Gustav, Inderberg, Else Marit, Wälchli, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587706/
https://ncbi.nlm.nih.gov/pubmed/28878363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11126-y
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