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An enhancer element 6 kb upstream of the mouse HNF4α1 promoter is activated by glucocorticoids and liver-enriched transcription factors

We have characterized a 700 bp enhancer element around –6 kb relative to the HNF4α1 transcription start. This element increases activity and confers glucocorticoid induction to a heterologous as well as the homologous promoters in differentiated hepatoma cells and is transactivated by HNF4α1, HNF4α7...

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Hlavní autoři: Bailly, Alain, Torres-Padilla, Maria Elena, Tinel, Antoine P., Weiss, Mary C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC55877/
https://ncbi.nlm.nih.gov/pubmed/11522818
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