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Identification of a p53 target, CD137L, that mediates growth suppression and immune response of osteosarcoma cells
p53 encodes a transcription factor that transactivates downstream target genes involved in tumour suppression. Although osteosarcoma frequently has p53 mutations, the role of p53 in osteosarcomagenesis is not fully understood. To explore p53-target genes comprehensively in calvarial bone and find ou...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5587585/ https://ncbi.nlm.nih.gov/pubmed/28878391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11208-x |
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