Identification of a p53 target, CD137L, that mediates growth suppression and immune response of osteosarcoma cells

p53 encodes a transcription factor that transactivates downstream target genes involved in tumour suppression. Although osteosarcoma frequently has p53 mutations, the role of p53 in osteosarcomagenesis is not fully understood. To explore p53-target genes comprehensively in calvarial bone and find ou...

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Pubblicato in:Sci Rep
Autori principali: Tsuda, Yusuke, Tanikawa, Chizu, Miyamoto, Takafumi, Hirata, Makoto, Yodsurang, Varalee, Zhang, Yao-zhong, Imoto, Seiya, Yamaguchi, Rui, Miyano, Satoru, Takayanagi, Hiroshi, Kawano, Hirotaka, Nakagawa, Hidewaki, Tanaka, Sakae, Matsuda, Koichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587585/
https://ncbi.nlm.nih.gov/pubmed/28878391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11208-x
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