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Quantitative T cell repertoire analysis by deep cDNA sequencing of T cell receptor α and β chains using next-generation sequencing (NGS)

Immune responses play a critical role in various disease conditions including cancer and autoimmune diseases. However, to date, there has not been a rapid, sensitive, comprehensive, and quantitative analysis method to examine T-cell or B-cell immune responses. Here, we report a new approach to chara...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Fang, Hua, Yamaguchi, Rui, Liu, Xiao, Daigo, Yataro, Yew, Poh Yin, Tanikawa, Chizu, Matsuda, Koichi, Imoto, Seiya, Miyano, Satoru, Nakamura, Yusuke
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368121/
https://ncbi.nlm.nih.gov/pubmed/25964866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.968467
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