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Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer
The aryl hydrocarbon receptor (AHR) plays crucial roles in inflammation, metabolic disorder, and cancer. However, the molecular mechanisms regulating AHR expression remain unknown. Here, we found that an orphan nuclear NR2E3 maintains AHR expression, and forms an active transcriptional complex with...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5587550/ https://ncbi.nlm.nih.gov/pubmed/28878246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11106-2 |
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