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Deregulation of NR2E3, an orphan nuclear receptor, by benzo(a)pyrene-induced oxidative stress is associated with histone modification status change of the estrogen receptor gene promoter

We previously reported that NR2E3, an orphan nuclear receptor, plays an important role in maintaining the basal expression of estrogen receptor α (ER) and that the NR2E3 level is highly correlated with the relapse-free survival of breast cancer patients. Here, we investigated the role of NR2E3 in be...

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Publicat a:Toxicol Lett
Autors principals: Khnal, Tilak, Kim, Dasom, Johnson, Abby, Choubey, Divaker, Kim, Kyounghyun
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524348/
https://ncbi.nlm.nih.gov/pubmed/26149760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2015.06.1708
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