Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation
We have constructed a stable cell line, human embryonal kidney 293M+, containing a lacZ reporter gene controlled by an in vitro methylated hormone-responsive enhancer. Methylation of the enhancer–promoter abolishes lacZ expression controlled by ponasterone A (an analogue of ecdysone). Ponasterone A-...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2001
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55875/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11522830/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.17.3603 |
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