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Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation
We have constructed a stable cell line, human embryonal kidney 293M+, containing a lacZ reporter gene controlled by an in vitro methylated hormone-responsive enhancer. Methylation of the enhancer–promoter abolishes lacZ expression controlled by ponasterone A (an analogue of ecdysone). Ponasterone A-...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC55875/ https://ncbi.nlm.nih.gov/pubmed/11522830 |
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