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Estradiol as a Targeted, Late-Line Therapy in Metastatic Breast Cancer with Estrogen Receptor Amplification

Estradiol is a major regulator of growth for the subset of breast cancers that express the estrogen receptor (ER, ESR1). Strategies to block ER action, via reduction of estradiol or direct inhibition of ER, have shown major success in the prevention and treatment of breast cancer. However, most ER-p...

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Detalhes bibliográficos
Publicado no:Cureus
Main Authors: Kota, Karthik, Brufsky, Adam, Oesterreich, Steffi, Lee, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: Cureus 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587405/
https://ncbi.nlm.nih.gov/pubmed/28924522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7759/cureus.1434
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