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Zoledronic acid effectiveness against breast cancer metastases - a role for estrogen in the microenvironment?

Zoledronic acid (ZA) is an imidazole-containing bisphosphonate that has been extensively studied as an osteoclast inhibitor. ZA decreases bone turnover and has been effective in limiting osteolysis in metastatic cancers, including breast cancer. Recent clinical trials that demonstrated enhancement o...

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Detalhes bibliográficos
Main Authors: Steinman, Richard A, Brufsky, Adam M, Oesterreich, Steffi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053096/
https://ncbi.nlm.nih.gov/pubmed/23014660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3223
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