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Zoledronic acid effectiveness against breast cancer metastases - a role for estrogen in the microenvironment?

Zoledronic acid (ZA) is an imidazole-containing bisphosphonate that has been extensively studied as an osteoclast inhibitor. ZA decreases bone turnover and has been effective in limiting osteolysis in metastatic cancers, including breast cancer. Recent clinical trials that demonstrated enhancement o...

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מידע ביבליוגרפי
Main Authors: Steinman, Richard A, Brufsky, Adam M, Oesterreich, Steffi
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053096/
https://ncbi.nlm.nih.gov/pubmed/23014660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3223
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