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Zoledronic acid effectiveness against breast cancer metastases - a role for estrogen in the microenvironment?

Zoledronic acid (ZA) is an imidazole-containing bisphosphonate that has been extensively studied as an osteoclast inhibitor. ZA decreases bone turnover and has been effective in limiting osteolysis in metastatic cancers, including breast cancer. Recent clinical trials that demonstrated enhancement o...

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Podrobná bibliografie
Hlavní autoři: Steinman, Richard A, Brufsky, Adam M, Oesterreich, Steffi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053096/
https://ncbi.nlm.nih.gov/pubmed/23014660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3223
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