Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells

Human pluripotent stem cells (hPSCs) are an important player in disease modeling and regenerative medicine. Nonetheless, multiple studies uncovered their inherent genetic instability upon prolonged culturing, where specific chromosomal aberrations provide cells with a growth advantage. These positiv...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Weissbein, Uri, Plotnik, Omer, Vershkov, Dan, Benvenisty, Nissim
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587343/
https://ncbi.nlm.nih.gov/pubmed/28837588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006979
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