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Genome-wide Screen for Culture Adaptation and Tumorigenicity-Related Genes in Human Pluripotent Stem Cells

Human pluripotent stem cells (hPSCs) acquire genetic changes during their propagation in culture that can affect their use in research and future therapies. To identify the key genes involved in selective advantage during culture adaptation and tumorigenicity of hPSCs, we generated a genome-wide scr...

詳細記述

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書誌詳細
出版年:iScience
主要な著者: Weissbein, Uri, Peretz, Mordecai, Plotnik, Omer, Yanuka, Ofra, Sagi, Ido, Golan-Lev, Tamar, Benvenisty, Nissim
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348297/
https://ncbi.nlm.nih.gov/pubmed/30660107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.12.031
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