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Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells
Human pluripotent stem cells (hPSCs) are an important player in disease modeling and regenerative medicine. Nonetheless, multiple studies uncovered their inherent genetic instability upon prolonged culturing, where specific chromosomal aberrations provide cells with a growth advantage. These positiv...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5587343/ https://ncbi.nlm.nih.gov/pubmed/28837588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006979 |
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