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M2SR, a novel live influenza vaccine, protects mice and ferrets against highly pathogenic avian influenza

The emergence of highly pathogenic avian influenza H5N1 viruses has heightened global concern about the threat posed by pandemic influenza. To address the need for a highly effective universal influenza vaccine, we developed a novel M2-deficient single replication (M2SR) influenza vaccine virus and...

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Bibliographic Details
Published in:Vaccine
Main Authors: Hatta, Yasuko, Boltz, David, Sarawak, Sally, Kawaoka, Yoshihiro, Neumann, Gabriele, Bilsel, Pamuk
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587242/
https://ncbi.nlm.nih.gov/pubmed/28668565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.06.039
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