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M2SR, a novel live Single Replication influenza virus vaccine, provides effective heterosubtypic protection in mice

Despite the annual public health burden of seasonal influenza and the continuing threat of a global pandemic posed by the emergence of highly pathogenic/pandemic strains, conventional influenza vaccines do not provide universal protection, and exhibit suboptimal efficacy rates, even when they are we...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Vaccine
Hauptverfasser: Sarawar, Sally, Hatta, Yasuko, Watanabe, Shinji, Dias, Peter, Neumann, Gabriele, Kawaoka, Yoshihiro, Bilsel, Pamuk
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038585/
https://ncbi.nlm.nih.gov/pubmed/27595896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.08.061
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