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An M2 Cytoplasmic Tail Mutant as a Live Attenuated Influenza Vaccine against Pandemic (H1N1) 2009 Influenza Virus

The 2009 influenza pandemic brought home the importance of vaccines in infection control. Previously, we demonstrated an M2 cytoplasmic tail mutant H5N1 influenza virus could serve as a live-attenuated vaccine. Here, we adapted that strategy, generating a mutant pandemic (H1N1) 2009 virus that grew...

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Detalhes bibliográficos
Main Authors: Hatta, Yasuko, Hatta, Masato, Bilsel, Pamuk, Neumann, Gabriele, Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132197/
https://ncbi.nlm.nih.gov/pubmed/21272601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.01.023
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