An M2 Cytoplasmic Tail Mutant as a Live Attenuated Influenza Vaccine against Pandemic (H1N1) 2009 Influenza Virus

The 2009 influenza pandemic brought home the importance of vaccines in infection control. Previously, we demonstrated an M2 cytoplasmic tail mutant H5N1 influenza virus could serve as a live-attenuated vaccine. Here, we adapted that strategy, generating a mutant pandemic (H1N1) 2009 virus that grew...

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Hauptverfasser: Hatta, Yasuko, Hatta, Masato, Bilsel, Pamuk, Neumann, Gabriele, Kawaoka, Yoshihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132197/
https://ncbi.nlm.nih.gov/pubmed/21272601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.01.023
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