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RecA filament maintains structural integrity using ATP-driven internal dynamics
At the core of homologous DNA repair, RecA catalyzes the strand exchange reaction. This process is initiated by a RecA loading protein, which nucleates clusters of RecA proteins on single-stranded DNA. Each cluster grows to cover the single-stranded DNA but may leave 1- to 2-nucleotide (nt) gaps bet...
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| Опубликовано в: : | Sci Adv |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Association for the Advancement of Science
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5587095/ https://ncbi.nlm.nih.gov/pubmed/28913424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1700676 |
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