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Matrix Metalloproteinase Inhibitor COL-3 Prevents the Development of Paclitaxel-Induced Hyperalgesia in Mice
OBJECTIVE: To study the potential of chemically modified tetracycline-3 (COL-3), a potent matrix metalloproteinase (MMP) inhibitor, to protect against the development of paclitaxel-induced painful neuropathy and its immunomodulatory effects. MATERIALS AND METHODS: The reaction latency to thermal sti...
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| Published in: | Med Princ Pract |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
S. Karger AG
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5586713/ https://ncbi.nlm.nih.gov/pubmed/22907189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000341710 |
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