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Coadministration of indomethacin and minocycline attenuates established paclitaxel-induced neuropathic thermal hyperalgesia: Involvement of cannabinoid CB(1) receptors

Taxanes such as paclitaxel, which are chemotherapeutic drugs, cause dose-dependent painful neuropathy in some patients. We investigated whether coadministration of minocycline and indomethacin produces antinociceptive effects in mice with paclitaxel-induced neuropathic thermal hyperalgesia and if th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Parvathy, Subramanian S., Masocha, Willias
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471734/
https://ncbi.nlm.nih.gov/pubmed/26085115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10541
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