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Inhibition of Mutant αB Crystallin‐Induced Protein Aggregation by a Molecular Tweezer
BACKGROUND: Compromised protein quality control causes the accumulation of misfolded proteins and intracellular aggregates, contributing to cardiac disease and heart failure. The development of therapeutics directed at proteotoxicity‐based pathology in heart disease is just beginning. The molecular...
Tallennettuna:
| Julkaisussa: | J Am Heart Assoc |
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| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
John Wiley and Sons Inc.
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5586456/ https://ncbi.nlm.nih.gov/pubmed/28862927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.006182 |
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