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Connected Gene Communities Underlie Transcriptional Changes in Cornelia de Lange Syndrome

Cornelia de Lange syndrome (CdLS) is a complex multisystem developmental disorder caused by mutations in cohesin subunits and regulators. While its precise molecular mechanisms are not well defined, they point toward a global deregulation of the transcriptional gene expression program. Cohesin is as...

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Podrobná bibliografie
Vydáno v:Genetics
Hlavní autoři: Boudaoud, Imène, Fournier, Éric, Baguette, Audrey, Vallée, Maxime, Lamaze, Fabien C., Droit, Arnaud, Bilodeau, Steve
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586368/
https://ncbi.nlm.nih.gov/pubmed/28679547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.202291
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