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Mutant cohesin affects RNA polymerase II regulation in Cornelia de Lange syndrome
In addition to its role in sister chromatid cohesion, genome stability and integrity, the cohesin complex is involved in gene transcription. Mutations in core cohesin subunits SMC1A, SMC3 and RAD21, or their regulators NIPBL and HDAC8, cause Cornelia de Lange syndrome (CdLS). Recent evidence reveals...
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| Опубликовано в: : | Sci Rep |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4652179/ https://ncbi.nlm.nih.gov/pubmed/26581180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16803 |
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