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A G protein‐coupled α7 nicotinic receptor regulates signaling and TNF‐α release in microglia
Acetylcholine activation of α7 nicotinic acetylcholine receptors (α7 nAChRs) in microglia attenuates neuroinflammation and regulates TNF‐α release. We used lipopolysaccharide to model inflammation in the microglial cell line EOC20 and examined signaling by the α7 nAChR. Co‐immunoprecipitation experi...
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| Publicado no: | FEBS Open Bio |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5586346/ https://ncbi.nlm.nih.gov/pubmed/28904864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12270 |
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