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Alpha 7 nicotinic receptors attenuate neurite development through calcium activation of calpain at the growth cone
The α7 nicotinic acetylcholine receptor (nAChR) is a ligand-gated ion channel that plays an important role in cellular calcium signaling contributing to synaptic development and plasticity, and is a key drug target for the treatment of neurodegenerative conditions such as Alzheimer’s disease. Here w...
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| Publicado no: | PLoS One |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5955587/ https://ncbi.nlm.nih.gov/pubmed/29768467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197247 |
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