Mucus-penetrating Nanosuspensions for Enhanced Delivery of Poorly Soluble Drugs to Mucosal Surfaces

Mucus-penetrating Nanosuspensions, consisting of pure hydrophobic therapeutics with dense muco-inert coatings that enable particles to effectively bypass the mucus barrier, demonstrate superior drug distribution and absorption at mucosal surfaces. With significantly increased drug load compared to p...

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Pubblicato in:Adv Healthc Mater
Autori principali: Yu, Tao, Choi, Woo-Jin, Anonuevo, Abraham, Chisholm, Jane, Pulicare, Sarah, Zhong, Weixi, Chen, Minmin, Fridley, Colleen, Lai, Samuel K., Ensign, Laura M., Suk, Jung Soo, Hanes, Justin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586074/
https://ncbi.nlm.nih.gov/pubmed/27717163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201600599
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