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Nanoparticle penetration of human cervicovaginal mucus: The effect of polyvinyl alcohol

Therapeutic nanoparticles must rapidly penetrate the mucus secretions lining the surfaces of the respiratory, gastrointestinal and cervicovaginal tracts to efficiently reach the underlying tissues. Whereas most polymeric nanoparticles are highly mucoadhesive, we previously discovered that a dense la...

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Detalhes bibliográficos
Main Authors: Yang, Ming, Lai, Samuel K., Yu, Tao, Wang, Ying-Ying, Happe, Christina, Zhong, Weixi, Zhang, Michael, Anonuevo, Abraham, Fridley, Colleen, Hung, Amy, Fu, Jie, Hanes, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194208/
https://ncbi.nlm.nih.gov/pubmed/25090196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.07.045
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