Knockout of the ATPase inhibitory factor 1 protects the heart from pressure overload-induced cardiac hypertrophy

Mitochondrial ATP synthase catalyzes the coupling of oxidative phosphorylation. Under pathological conditions, ATP synthase hydrolyzes ATP to replenish protons from the matrix into the intermembrane space, sustaining mitochondrial membrane potential. ATPase inhibitory factor 1 (IF1) is a nuclear-enc...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yang, Kevin, Long, Qinqiang, Saja, Kamalamma, Huang, Fengyuan, Pogwizd, Steven M., Zhou, Lufang, Yoshida, Masasuke, Yang, Qinglin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585346/
https://ncbi.nlm.nih.gov/pubmed/28874825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11251-8
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