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Structural and pharmacological basis for the induction of mitochondrial biogenesis by formoterol but not clenbuterol
Mitochondrial dysfunction is associated with numerous acute and chronic degenerative diseases. The beta-2 adrenergic receptor (β(2)AR) agonist formoterol induces mitochondrial biogenesis (MB), but other β(2)AR agonists, such as clenbuterol, do not. We sought to identify the MB signaling pathway of f...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5585315/ https://ncbi.nlm.nih.gov/pubmed/28874749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11030-5 |
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