CRISPR-Cas9 mediated one-step disabling of pancreatogenesis in pigs

Genome editing using programmable nucleases has revolutionized biomedical research. CRISPR-Cas9 mediated zygote genome editing enables high efficient production of knockout animals suitable for studying development and relevant human diseases. Here we report efficient disabling pancreatogenesis in p...

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Pubblicato in:Sci Rep
Autori principali: Wu, Jun, Vilarino, Marcela, Suzuki, Keiichiro, Okamura, Daiji, Bogliotti, Yanina Soledad, Park, Insung, Rowe, Joan, McNabb, Bret, Ross, Pablo Juan, Belmonte, Juan Carlos Izpisua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585254/
https://ncbi.nlm.nih.gov/pubmed/28874671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08596-5
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