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CRISPR/Cas9 and TALE: beyond cut and paste

Nuclease-based genome editing has proven to be a powerful and promising tool for disease modeling and gene therapy. Recent advances in CRISPR/Cas and TALE indicate that they could also be used as a targeted regulator of gene expression, as well as being utilized for illuminating specific chromosomal...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Deng, Liping, Ren, Ruotong, Wu, Jun, Suzuki, Keiichiro, Izpisua Belmote, Juan Carlos, Liu, Guang-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348244/
https://ncbi.nlm.nih.gov/pubmed/25722052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-015-0137-5
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