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T-bet, but not Gata3, overexpression is detrimental in a neurotropic viral infection
Intracerebral Theiler’s murine encephalomyelitis virus (TMEV) infection in mice induces inflammatory demyelination in the central nervous system. Although C57BL/6 mice normally resistant to TMEV infection with viral clearance, we have previously demonstrated that RORγt-transgenic (tg) C57BL/6 mice,...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5585213/ https://ncbi.nlm.nih.gov/pubmed/28874814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10980-0 |
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