The Dietary Constituent Falcarindiol Promotes Cholesterol Efflux from THP-1 Macrophages by Increasing ABCA1 Gene Transcription and Protein Stability

We report increased cholesterol efflux from macrophages in the presence of falcarindiol, an important dietary constituent present in commonly used vegetables and medicinal plants. Falcarindiol (3–20 μM) increased cholesterol efflux from THP-1-derived macrophages. Western blot analysis showed an incr...

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Publicado en:Front Pharmacol
Autores principales: Wang, Limei, Palme, Veronika, Schilcher, Nicole, Ladurner, Angela, Heiss, Elke H., Stangl, Herbert, Bauer, Rudolf, Dirsch, Verena M., Atanasov, Atanas G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585181/
https://ncbi.nlm.nih.gov/pubmed/28919859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00596
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