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The Dietary Constituent Falcarindiol Promotes Cholesterol Efflux from THP-1 Macrophages by Increasing ABCA1 Gene Transcription and Protein Stability

We report increased cholesterol efflux from macrophages in the presence of falcarindiol, an important dietary constituent present in commonly used vegetables and medicinal plants. Falcarindiol (3–20 μM) increased cholesterol efflux from THP-1-derived macrophages. Western blot analysis showed an incr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Pharmacol
Prif Awduron: Wang, Limei, Palme, Veronika, Schilcher, Nicole, Ladurner, Angela, Heiss, Elke H., Stangl, Herbert, Bauer, Rudolf, Dirsch, Verena M., Atanasov, Atanas G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585181/
https://ncbi.nlm.nih.gov/pubmed/28919859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00596
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