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The Dietary Constituent Falcarindiol Promotes Cholesterol Efflux from THP-1 Macrophages by Increasing ABCA1 Gene Transcription and Protein Stability

We report increased cholesterol efflux from macrophages in the presence of falcarindiol, an important dietary constituent present in commonly used vegetables and medicinal plants. Falcarindiol (3–20 μM) increased cholesterol efflux from THP-1-derived macrophages. Western blot analysis showed an incr...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Wang, Limei, Palme, Veronika, Schilcher, Nicole, Ladurner, Angela, Heiss, Elke H., Stangl, Herbert, Bauer, Rudolf, Dirsch, Verena M., Atanasov, Atanas G.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585181/
https://ncbi.nlm.nih.gov/pubmed/28919859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00596
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