Altered Immune Activation and IL-23 Signaling in Response to Candida albicans in Autoimmune Polyendocrine Syndrome Type 1

OBJECTIVE: Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare, childhood onset disease caused by mutations in the autoimmune regulator (AIRE) gene. Chronic mucocutaneous candidiasis (CMC) is one of the three major disease components and is, to date, mainly explained by the presence of neutra...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Bruserud, Øyvind, Bratland, Eirik, Hellesen, Alexander, Delaleu, Nicolas, Reikvam, Håkon, Oftedal, Bergithe E., Wolff, Anette S. B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585148/
https://ncbi.nlm.nih.gov/pubmed/28919897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01074
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