Altered Immune Activation and IL-23 Signaling in Response to Candida albicans in Autoimmune Polyendocrine Syndrome Type 1

OBJECTIVE: Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare, childhood onset disease caused by mutations in the autoimmune regulator (AIRE) gene. Chronic mucocutaneous candidiasis (CMC) is one of the three major disease components and is, to date, mainly explained by the presence of neutra...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bruserud, Øyvind, Bratland, Eirik, Hellesen, Alexander, Delaleu, Nicolas, Reikvam, Håkon, Oftedal, Bergithe E., Wolff, Anette S. B.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585148/
https://ncbi.nlm.nih.gov/pubmed/28919897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01074
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