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Altered Immune Activation and IL-23 Signaling in Response to Candida albicans in Autoimmune Polyendocrine Syndrome Type 1

OBJECTIVE: Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare, childhood onset disease caused by mutations in the autoimmune regulator (AIRE) gene. Chronic mucocutaneous candidiasis (CMC) is one of the three major disease components and is, to date, mainly explained by the presence of neutra...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Bruserud, Øyvind, Bratland, Eirik, Hellesen, Alexander, Delaleu, Nicolas, Reikvam, Håkon, Oftedal, Bergithe E., Wolff, Anette S. B.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585148/
https://ncbi.nlm.nih.gov/pubmed/28919897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01074
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