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Accumulation of undegraded autophagosomes by expression of dominant-negative STX17 (syntaxin 17) mutants

Macroautophagy/autophagy, which is one of the main degradation systems in the cell, is mediated by a specialized organelle, the autophagosome. Purification of autophagosomes before fusion with lysosomes is important for both mechanistic and physiological studies of the autophagosome. Here, we report...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Autophagy
Hauptverfasser: Uematsu, Masaaki, Nishimura, Taki, Sakamaki, Yuriko, Yamamoto, Hayashi, Mizushima, Noboru
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584865/
https://ncbi.nlm.nih.gov/pubmed/28598244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1327940
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