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Repression of the F-box protein Skp2 is essential for actin damage-induced tetraploid G1 arrest
We previously reported that p53 plays a role as a key regulator in the tetraploid G1 checkpoint, which is activated by actin damage-induced cytokinesis blockade and then prevents uncoupled DNA replication and nuclear division without cytokinesis. In this study, we investigated a role of Skp2, which...
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| Publicat a: | BMB Rep |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Korean Society for Biochemistry and Molecular Biology
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584746/ https://ncbi.nlm.nih.gov/pubmed/28648144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2017.50.7.063 |
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