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Role of the F-box protein Skp2 in lymphomagenesis

The F-box protein Skp2 (S-phase kinase-associated protein 2) positively regulates the G(1)-S transition by controlling the stability of several G(1) regulators, such as the cell cycle inhibitor p27. We show here that Skp2 expression correlates directly with grade of malignancy and inversely with p27...

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Detalhes bibliográficos
Main Authors: Latres, Esther, Chiarle, Roberto, Schulman, Brenda A., Pavletich, Nikola P., Pellicer, Angel, Inghirami, Giorgio, Pagano, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC30169/
https://ncbi.nlm.nih.gov/pubmed/11226270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.041475098
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