Wwox Deletion in Mouse B Cells Leads to Genomic Instability, Neoplastic Transformation, and Monoclonal Gammopathies

WWOX (WW domain containing oxidoreductase) expression loss is common in various cancers and characteristic of poor prognosis. Deletions, translocations, and loss of expression affecting the WWOX gene are a common feature of various B cell neoplasms such as certain B cell lymphomas and multiple myelo...

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Autors principals:	Kevin M. McBride, Hyunsuk Kil, Yunxiang Mu, Joshua B. Plummer, Jaeho Lee, Maciej J. Zelazowski, Manu Sebastian, Martin C. Abba, C. Marcelo Aldaz
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2019-06-01
Col·lecció:	Frontiers in Oncology
Matèries:	Wwox B cells monoclonal gammopathies plasmacytomas multiple myeloma genomic instability
Accés en línia:	https://www.frontiersin.org/article/10.3389/fonc.2019.00517/full
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