QR-Code

Wwox Deletion in Mouse B Cells Leads to Genomic Instability, Neoplastic Transformation, and Monoclonal Gammopathies

WWOX (WW domain containing oxidoreductase) expression loss is common in various cancers and characteristic of poor prognosis. Deletions, translocations, and loss of expression affecting the WWOX gene are a common feature of various B cell neoplasms such as certain B cell lymphomas and multiple myelo...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Kevin M. McBride, Hyunsuk Kil, Yunxiang Mu, Joshua B. Plummer, Jaeho Lee, Maciej J. Zelazowski, Manu Sebastian, Martin C. Abba, C. Marcelo Aldaz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019-06-01
Schriftenreihe:Frontiers in Oncology
Schlagworte:
Wwox
B cells
monoclonal gammopathies
plasmacytomas
multiple myeloma
genomic instability
Online-Zugang:https://www.frontiersin.org/article/10.3389/fonc.2019.00517/full
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge