The role of pharmacologic modulation of autophagy on anal cancer development in an HPV mouse model of carcinogenesis

Autophagy is an intracellular, catabolic process that maintains cellular health. We examined the response of pharmacologic modulation of autophagy in an HPV mouse model of anal carcinogenesis. K14E6/E7 mice were treated with the topical carcinogen DMBA weekly and assessed for tumors over 20 weeks. C...

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Bibliographic Details
Published in:Virology
Main Authors: Rademacher, Brooks L., Matkowskyj, Kristina A., Meske, Louise M., Romero, Alexis, Sleiman, Hana, Carchman, Evie H.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584602/
https://ncbi.nlm.nih.gov/pubmed/28431282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.04.007
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