Laddar...

Topical Application of a Dual PI3K/mTOR Inhibitor Prevents Anal Carcinogenesis in an HPV Mouse Model of Anal Cancer

Human papillomavirus (HPV) infection is the major risk factor for anal dysplasia that may progress to squamous cell carcinoma of the anus (SCCA). We have previously shown that systemic administration of a PI3K/mTOR inhibitor (BEZ235), an autophagic inducer, results in decreased SCCA in our HPV mouse...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Eur J Cancer Prev
Huvudupphovsmän: Rademacher, Brooks L., Matkowskyj, Kristina A., LaCount, Emily D., Carchman, Evie H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751036/
https://ncbi.nlm.nih.gov/pubmed/30888976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CEJ.0000000000000505
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!