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Topical Application of a Dual PI3K/mTOR Inhibitor Prevents Anal Carcinogenesis in an HPV Mouse Model of Anal Cancer
Human papillomavirus (HPV) infection is the major risk factor for anal dysplasia that may progress to squamous cell carcinoma of the anus (SCCA). We have previously shown that systemic administration of a PI3K/mTOR inhibitor (BEZ235), an autophagic inducer, results in decreased SCCA in our HPV mouse...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Eur J Cancer Prev |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6751036/ https://ncbi.nlm.nih.gov/pubmed/30888976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CEJ.0000000000000505 |
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