The role of pharmacologic modulation of autophagy on anal cancer development in an HPV mouse model of carcinogenesis

Autophagy is an intracellular, catabolic process that maintains cellular health. We examined the response of pharmacologic modulation of autophagy in an HPV mouse model of anal carcinogenesis. K14E6/E7 mice were treated with the topical carcinogen DMBA weekly and assessed for tumors over 20 weeks. C...

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Gepubliceerd in:Virology
Hoofdauteurs: Rademacher, Brooks L., Matkowskyj, Kristina A., Meske, Louise M., Romero, Alexis, Sleiman, Hana, Carchman, Evie H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584602/
https://ncbi.nlm.nih.gov/pubmed/28431282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.04.007
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