The role of MAP2 kinases and p38 kinase in acute murine liver injury models

c-Jun N-terminal kinase (JNK) mediates hepatotoxicity through interaction of its phospho-activated form with a mitochondrial outer membrane protein, Sh3bp5 or Sab, leading to dephosphorylation of intermembrane Src and consequent impaired mitochondrial respiration and enhanced ROS release. ROS produc...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Cell Death Dis
Autores principales: Zhang, Jun, Min, Robert W M, Le, Khanh, Zhou, Sheng, Aghajan, Mariam, Than, Tin A, Win, Sanda, Kaplowitz, Neil
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584575/
https://ncbi.nlm.nih.gov/pubmed/28661486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.295
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares